Proteomics is the science that studies the composition and changes of proteins in cells, tissues, or organisms based on the study of proteomics. This includes research on protein expression levels, post translational modifications, and protein-protein interactions, focusing on dynamically describing gene regulation, quantitatively measuring the protein levels of gene expression, identifying the effects of diseases, drugs, and other factors on life processes, and explaining the mechanisms of gene expression regulation. Proteomics can be applied to research fields such as protein function, biomarkers, disease mechanisms, drug targets, crop development, food safety and nutrition, and the exploration of novel virus inhibitors.
Epigenetics refers to the heritable changes in gene expression, regulation, and traits (fundamentally due to differences in epigenetic modifications) without altering the nucleic acid (DNA) sequence, that is, changing the phenotype without altering the genotype. Epigenetics can be used to study the physiological and pathological changes of a certain tissue. Combined with single-cell sequencing technology, it can be used to study the pathogenesis, early diagnosis, and late control of tumor diseases.Epigenomics sequencing is a technology based on a high-throughput sequencing platform that studies heritable changes in gene expression and regulation. According to the research content, epigenomics can be classified into two categories: chemical modification of DNA/RNA, and the interaction between DNA/RNA and proteins.
